(S)-HDAC-42

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Cat No.

CEI-0998

Description

S)-HDAC-42 is a strong inhibitor of HDACs. It decreases the viability of prostate cancer cell lines by increasingthe expression of p21 and the acetylation of histone H3 while decreasing Akt phosphorylation and Bcl-XL expression. The inhibitor suppresses the growth of PC-3 tumor xenografts, reducing levels of phospho-Akt and Bcl-XL protein in tumors.

Abbr

(S)-HDAC-42(HDACs)

Appearance

A crystalline solid.

CAS_No

935881-37-1

Molecular Weight

312.4

Purity

>95%

Storage

Store at or below -20 centigrade for up to two years.

Targets

HDACs

IC50

16 nM

Molecular Formula

C8H20N2O3

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Project Description:

For research and industrial use only, not for personal medicinal use.

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