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11-oxo-β-amyrin 30-oxidase

Cat No.
EXWM-0771
Description
A heme-thiolate protein (cytochrome P-450). The enzyme is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin in the plant Glycyrrhiza uralensis (licorice). The enzyme from the plant Medicago truncatula can also hydroxylate β-amyrin.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
CYP72A; CYP72A154
Reaction
11-oxo-β-amyrin + 3 O2 + 3 NADPH + 3 H+ = glycyrrhetinate + 3 NADP+ + 4 H2O (overall reaction); (1a) 11-oxo-β-amyrin + O2 + NADPH + H+ = 30-hydroxy-11-oxo-β-amyrin + NADP+ + H2O; (1b) 30-hydroxy-11-oxo-β-amyrin + O2 + NADPH + H+ = glycyrrhetaldehyde + NADP+ + 2 H2O; (1c) glycyrrhetaldehyde + O2 + NADPH + H+ = glycyrrhetinate + NADP+ + H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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