2-Methyl-L-cysteine Hydrochloride

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Cat No.

CEGZ-6926

Description

2-Methyl-L-cysteine hydrochloride is the hydrochloride salt of an α-methylated cysteine analogue in which the α-hydrogen is replaced by a methyl group, generating a quaternary α-carbon. The free thiol side chain retains the characteristic reactivity of cysteine.

Applications

Used as a building block and intermediate in peptide and medicinal chemistry research for the preparation of α-methylated, protease-resistant peptide analogues containing thiol functionality.

Product Overview

α-Methylation of cysteine restricts local backbone conformation and increases resistance to enzymatic degradation, while the thiol group remains available for disulfide formation or alkylation, making this derivative useful in the design of constrained, stabilized peptides.

CAS_No

148766-37-4

Molecular Weight

171.65

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

α-methyl-L-cysteine hydrochloride; L-2-amino-2-methyl-3-mercaptopropanoic acid hydrochloride

Molecular Formula

C4H10ClNO2S

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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