4-hydroxythreonine-4-phosphate dehydrogenase

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Cat No.

EXWM-0168

Description

The product of the reaction undergoes decarboxylation to give 3-amino-2-oxopropyl phosphate. The enzyme is part of the biosynthesis pathway of the coenzyme pyridoxal 5'-phosphate found in anaerobic bacteria.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 1.1.1.262

CAS_No

230310-36-8

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

NAD+-dependent threonine 4-phosphate dehydrogenase; L-threonine 4-phosphate dehydrogenase; 4-(phosphohydroxy)-L-threonine dehydrogenase; PdxA; 4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase

Reaction

4-phosphonooxy-L-threonine + NAD+ = 3-amino-2-oxopropyl phosphate + CO2 + NADH + H+ (overall reaction); (1a) 4-phosphonooxy-L-threonine + NAD+ = (2S)-2-amino-3-oxo-4-phosphonooxybutanoate + NADH + H+; (1b) (2S)-2-amino-3-oxo-4-phosphonooxybutanoate = 3-amino-2-oxopropyl phosphate + CO2 (spontaneous)

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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