4-Methylumbelliferone sodium salt

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Cat No.

CSUB-0670

Description

4-Methylumbelliferone sodium salt is a selective inhibitor of Hyaluronan (HA) synthesis. HA is a major component in the metastasis of malignant tumors. Studies indicate that in the presence of 4-Methylumbelliferone sodium salt cell proliferation, migration, and growth are inhibited, while apoptosis is induced. In addition, the motility and cell growth was inhibited in fibroblast cell line NIH/3T3 (sc-2210). 4-Methylumbelliferone sodium salt is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis. It is also believed that 4-Methylumbelliferone sodium salt can suppress the expression of HA-synthase.

Applications

β-Galactosidase activity in solution can be revealed by the fluorogenic substrate 4-methylumbelliferone. It is also a selective inhibitor of Hyaluronan (HA) synthesis and

Form

Solid

CAS_No

5980-33-6

Molecular Weight

198.15

Purity

>98%

Storage

Store at room temperature

Synonyms

Cantabiline sodium; 7-Hydroxy-4-methylcoumarin

Molecular Formula

C10H7O3•Na

Solubility

Soluble in water

Substrates

Mannosidase

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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