4-MU β-D-galactopyranoside-6-sulfate

inquiry

Cat No.

NATZ-100

Description

4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.

Form

A crystalline solid

CAS_No

206443-06-3

Molecular Weight

440.4

Purity

98%

Storage

-20°C

Synonyms

4-MU β-D-galactopyranoside-6-sulfate
4-Methylumbelliferyl Gal-6S
4-MU-Gal-6S

Molecular Formula

C16H17O11S • Na

Name:

Email *

Phone:*

Company/Institution:

Country or Region:

Quantity:

Services & Products Interested *

Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Products

Online Inquiry