6BIO

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Cat No.

CEI-0951

Description

Scientific Background Potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM. The first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Promotes proliferation in mammalian cardiomyocytes. A potent inhibitor of malignant lymphoid cell proliferation.

Abbr

6BIO(GSK3)

Alias

(2'Z, 3'E)-6-Bromoindirubin-3'-oxime

Appearance

Purple powder

Product Overview

GSK3 inhibitor

CAS_No

667463-62-9

Molecular Weight

356.2

Purity

98% (TLC: 5% CH3OH3 in CH2Cl2, Rf=0.43); NMR (Conforms)

Synonyms

(2'Z,3'E)-6-Bromoindirubin-3'-oxime

Targets

GSK3

Molecular Formula

C16H10BrN3O2

Melting Point

263-265ºC

Solubility

Soluble in DMSO (15 mg/ml); or Ethanol (4 mg/ml, warm)

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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