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Cholesterol Linoleate

Cat No.
CHL-0100
Description
Cholesteryl linoleate is a major cholesterol ester found associated with the neutral core of low density lipoprotein. Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters. The enzyme acid cholesteryl ester hydrolase is responsible for the hydrolysis of cholesteryl esters; a defective enzyme can result in the formation of atherosclerotic lesions in humans.
Abbr
Cholesterol Linoleate
Applications
Cholesteryl linoleate was cosonicated with cholesterol to prepare dispersions were prepared to study the cholesterol to phospholipid ratio in red blood cell membrane. It was used as HPLC standard in the analysis of rat liver lipoproteins.
CAS No.
604-33-1
Molecular Weight
649.1
Purity
>97.0%
Structure
C45H76O2
Storage
at −20°C
Preparation Instructions
Cholesteryl linoleate yields clear, colorless solution in chloroform at 100 mg/ml.
Synonyms
3β-Hydroxy-5-cholestene 3-linoleate; 5-Cholesten-3β-ol 3-linoleate; Cholesteryl 9,12-octadecadienoate; Cholesteryl octadecadienoate; Linoleic Acid Cholesterol Ester
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