Description
Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. It is important for the diffusion of toxins and proteins produced by S. pyogenes.
Abbr
Hyaluronate Lyase, Recombinant (Streptococcus pyogenes)
Species
Streptococcus pyogenes
Form
ammonium sulfate suspension
Enzyme Commission Number
EC 4.2.2.1
Activity
> 8.0 units/mg protein (5.0-15.0 mg/mL)
Unit Definition
1 U corresponds to the amount of enzyme which liberates 1 μmol unsaturated disaccharides per minute at pH 6.0 and 37°C from hyaluronic acid.
Synonyms
hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase
