Description
Ketoreductase reduces 4-chloroacetoacetate with NADPH as a cosubstrate.
Abbr
Ketoreductase, Recombinant
Applications
Ketoreductases are used to study the stereospecificity of ketoreductase domains. They may be used to reduce precursors of α-chloroalcohols, which are synthetic intermediates for various pharmaceutical compounds. This product is recombinant and expressed in E. coli at > 2.2 units/mg.
Package
Bottomless glass bottle. Contents are inside inserted fused cone.
Enzyme Commission Number
EC 1.1.1.2
Activity
> 0.2 units/mg； > 2.2 units/mg
Unit Definition
1 U corresponds to the amount of enzyme which reduces 1 μmol 4-chloroacetoacetate per minute at pH 6.0 and 25°C (cosubstrate NADPH).
Synonyms
Ketoreductase; EC 1.1.1.2; 9028-12-0
