Products

Enzymes for Research, Diagnostic and Industrial Use

Native Human Calprotectin

Cat No.
NATE-1597
Description
Calprotectin is an important calcium signalling protein involved in wound healing. A complex of both MRP14 and MRP8, calprotectin plays a role in vascular inflammation and leukocyte recruitment. This 36kDA complex is a calcium and zinc- binding protein that represents 60% of cytosolic proteins of granulocytes. Classed as a damage associated molecular pattern marker it displays antimicrobial protective properties.
Extracellular release of calprotectin during cell damage/stress can be used as a marker for intestinal inflammation. There is growing evidence that faecal calprotectin correlates with mucosal disease activity which can be utilised as a monitoring response to relapse and treatments in inflammatory bowel disease. Measuring the concentration of calprotectin in faeces is an indirect measure of neutrophil infiltrate in the bowel mucosa.
Abbr
Calprotectin, Native (Human)
Source
Human Leukocytes
Species
Human
Applications
Faecal calprotectin determination has been shown to be useful in the diagnosis and management of inflammatory bowel disease.
Molecular Weight
Heterotetramer containing two 8 kDa and two 14 kDa subunits
Purity
>90% by SDS‐polyacrylamide electrophoresis, Purified using conventional chromatography procedures
Synonyms
Protein S100; calgranulin; leucocyte L1 complex; migration inhibitory factor‐related protein; MRP8/14; S100 calcium‐binding protein
Download Datasheet:



Inquiry
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: