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Native Human Catalase

Cat No.
NATE-0108
Description
Catalase activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. It functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids. Catalase has also been used to study the role reactive oxygen species play in gene expression and apoptosis.
Abbr
CAT, Native (Human)
Alias
Catalase; CAT
Source
Human erythrocytes
Species
Human
Product Overview
Protein determined by biuret
Form
buffered aqueous solution. Solution in 50 mM Tris, pH 8.0
Enzyme Commission Number
EC 1.11.1.6
Activity
> 30,000 units/mg protein
CAS No.
9001-05-2
Molecular Weight
tetramer mol wt ~250 kDa
Purity
> 90% (SDS-PAGE)
Unit Definition
One unit will decompose 1.0 μmole of H2O2 per min at pH 7.0 at 25°C, while the H2O2 conc. falls from 10.3 to 9.2 mM, measured by the rate of decrease of A240.
Storage
−20°C
Pathway
Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Folate Metabolism, organism-specific biosystem; FoxO family signaling, organism-specific biosystem; Glyoxylate and dicarboxylate metabolism, organism-specific biosystem; Glyoxylate and dicarboxylate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem
Function
NADP binding; aminoacylase activity; catalase activity; catalase activity; heme binding; metal ion binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity
Synonyms
EC 1.11.1.6; Catalase; catalase; equilase; caperase; optidase; catalase-peroxidase; CAT; H2O2:H2O2 oxidoreductase; 9001-05-2
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