Description
Prepared from Human Factor IX by activation with Bovine Factor XIa. This Bovine Factor XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXaβ.
Abbr
Factor IXa β, Native (Human)
Buffer
20 mM Tris-HCl/ 0.1 M NaCl/ pH 7.4
Synonyms
Human Factor IXa Beta; Factor IXa Beta; Factor IXa