AG-1024 (Tyrphostin)

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Cat No.

CEI-0035

CAS_No

65678-07-1

Molecular Weight

305.17

Purity

>99%

Storage

2 years at -20 centigrade

Targets

IGF-1R

Molecular Formula

C14H13BrN2O

Solubility

In vitro

Tyrphostin AG1024 can inhibit IGF-1R with IC50 of around 400 nM. By inhibiting insulin-like growth factor 1 receptor and insulin receptor, Tyrphostin AG1024 arrested melanoma cell growth. Tyrphostin AG1024 inhibited the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and restored pRb tumor suppressive function.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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