AG-1296

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Cat No.

CEI-0954

Description

A potent inhibitor of PDGF receptor tyrosine kinase (PDGFRalpha and beta), IC50=1 µM. Also inhibits FGF receptor tyrosine kinase, c-kit and FLT3 and reverses transformation induced by activated FLT3. Induces apoptosis in a small-cell lung cancer cell line (H526). Cell permeable.

Abbr

AG-1296(PDGFRB)

Alias

6, 7-Dimethoxy-3-phenylquinoxaline

Product Overview

PDGFR Inhibitor

CAS_No

146535-11-7

Molecular Weight

266.3

Purity

>98% (TLC); NMR (Conforms)

Synonyms

6,7-Dimethoxy-3-phenylquinoxaline

Targets

PDGFR

Molecular Formula

C16H14N2O2

Solubility

May be dissolved in DMSO

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Project Description:

For research and industrial use only, not for personal medicinal use.

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