AG-1478

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Cat No.

CEI-0955

Description

Potent and selective inhibitor of the EGFR kinase IC50 = 3 nM. Inhibits proliferation of a variety human cancer cell lines. Reduces pulmonary fibrosis in a rat model. Cell permeable.

Abbr

AG-1478(EGFR)

Alias

1. N-(3-Chlorophenyl)-6, 7-dimethoxy-4-quinazolinanine

Appearance

Off white powder

Product Overview

EGFR inhibitor

CAS_No

175178-82-2

Molecular Weight

315.8

Purity

>98% (TLC); NMR (Conforms)

Synonyms

1. N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine

Targets

EGFR

Molecular Formula

C16H14ClN3O2

Melting Point

177-178ºC

Solubility

May be dissolved in DMSO (30 mg/ml); or Ethanol (10 mg/ml, warm)

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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