AMG-47a

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Cat No.

CEI-1083

Description

AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.

Abbr

AMG-47a(LCK)

Alias

RP4-675E8.4, LSK, YT16, p56lck, pp58lck

Product Overview

Inhibitor of Lck and T cell

CAS_No

882663-88-9

Molecular Weight

535.56

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

-20 centigrade

Synonyms

RP4-675E8.4, LSK, YT16, p56lck, pp58lck

Targets

Lck

Molecular Formula

C29H28F3N5O2

Chemical Name

3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)-4-methylbenzamide

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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