Amidepsine D, Humcola sp.

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Cat No.

CEI-0458

Description

An inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50 = 17.5 µM) and Raji cells (IC50 = 2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

Appearance

White to off-white solid

Product Overview

A diacylglycerol acyltransferase (DGAT) inhibitor

CAS_No

79786-34-8

Molecular Weight

366.24

Purity

>95% by HPLC

Storage

-20 centigrade

Targets

DGAT1

Molecular Formula

C 26 H 24 NO 10

Chemical Name

N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoic acid

Solubility

DMSO

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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