AminoAcylase-1 from Human, Recombinant

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Cat No.

NATE-0810

Description

Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.

Abbr

ACY1, Recombinant (Human)

Alias

ACY1

Source

E. coli

Species

Human

Appearance

Sterile Filtered clear solution.

Product Overview

ACY1 Recombinant Human produced in E. coli is a single, non-glycosylated polypeptide chain containing 428 amino acids (1-408 a.a.) and having a molecular mass of 48 kDa. The ACY1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Molecular Weight

48 kDa

Purity

Greater than 90.0% as determined by SDS-PAGE.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Buffer

The ACY1 solution (0.5mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.

Synonyms

N-acyl-L-amino-acid amidohydrolase; ACY-1, ACY1D; ACYLASE; ACY1; aminoacylase 1; aminoacylase I; dehydropeptidase II; histozyme; hippuricase; benzamidase; acylase I; hippurase; amido acid deacylase; L-aminoacylase; acylase; aminoacylase; L-amino-acid acylase; α-N-acylaminoacid hydrolase; long acyl amidoacylase; short acyl amidoacylase

"ACY1" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1835	L-Aminoacylase (Crude Enzyme)	EC 3.5.1.14	9012-37-7	E. coli	Inquiry
NATE-0029	Native Aspergillus melleus Acylase I	EC 3.5.1.14	9012-37-7	Aspergillus melleus	Inquiry
NATE-0030	Acylase I from Aspergillus sp., Immobilized on Eupergit C	EC 3.5.1.14	9012-37-7	Aspergillus sp	Inquiry
NATE-0031	Native Porcine Acylase I	EC 3.5.1.14	9012-37-7	Porcine kidney	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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