Bafilomycin A1

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Cat No.

CEI-0697

Description

A highly potent and selective inhibitor of vacuolar H⁺-ATPases (V-ATPases) in vitro. It is effective in nanomolar concentrations in animal cells, plant cells and microorganisms; also selective over other ATP hydrolyzing enzymes such as F-ATPases, Ca²⁺ATPases, Na⁺K⁺ATPases and plasma membrane H⁺-ATPases. Also prevents autophagy at a late stage by inhibiting fusion between autophagosomes and lysosomes.

Appearance

White solid

Product Overview

An inhibitor of vacuolar H+-ATPases (V-ATPases)

CAS_No

88899-55-2

Molecular Weight

149.15

Purity

>98%

Storage

-20 centigrade

Targets

ATP6V0A4

Molecular Formula

C₃₅H₅₈O₉

Solubility

DMSO (50 mM)

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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