BAY 11-7082

inquiry

Cat No.

CEI-0590

Description

Potential anti-inflammatory agent. Selectively and irreversibly inhibits NF-κB activation by blocking TNF-α-induced phosphorylation of IκB-α without affecting constitutive IκB-α phosphorylation. Inhibits the TNF-α-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells with IC50 values of 5-10 µM.

Appearance

Colorless film

Product Overview

A NF-κB activation inhibitor

CAS_No

19542-67-7

Molecular Weight

622.84

Purity

>95% by HPLC

Storage

-20 centigrade

Targets

NFKB1

Molecular Formula

C₁₀H₉NO₂S

Chemical Name

(E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile

Solubility

DMSO

Shipping Conditions

Gel pack

First Name:

Last Name:

Email *

Phone Number:

Company/Institution:

Country or Region:

Quantity:

Services & Products of Interested

Project Description:

For research and industrial use only, not for personal medicinal use.

Products

Online Inquiry