Biotin-IETD-FMK

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Cat No.

CEI-0441

Description

A synthetic peptide that irreversibly inhibits activity of caspase-8 and related caspases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Alias

Biotin-IETD-FMK, IETD-FMK, Biotin-

Appearance

White to off-white solid

Product Overview

A Caspase-8 inhibitor

Molecular Weight

489.4

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

Biotin-IETD-FMK, IETD-FMK, Biotin-

Targets

CASP8

Molecular Formula

C₃₈H₆₂FN₇O₁₂S

Solubility

DMSO (~ 15 mg/ml) or Ethanol (~ 10 mg/ml)

Shipping Conditions

Gel pack

Amino Acid Sequence

Biotin-Ile-Glue(OMe)-Thr-Asp(OMe)-FMK

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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