BML-259

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Cat No.

CEI-0959

Description

Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM). Protects cells against NAC-amyloid-induced cell death. Cell permeable.

Abbr

BML-259 (CDK5, CDK5R1)

Alias

N-(5-Isopropylthiazol-2-yl) phenylacetamide

Appearance

White powder

Product Overview

CDK5/p25 inhibitor

CAS_No

267654-00-2

Molecular Weight

260.4

Purity

>98% (TLC: 5% CH3OH/CH2Cl2; Rf=0.46); NMR (Conforms)

Synonyms

N-(5-Isopropylthiazol-2-yl) phenylacetamide

Targets

CDK5/p25

Molecular Formula

C14H16N2OS

Melting Point

150-152ºC

Solubility

May be dissolved in DMSO (>25 mg/ml) or DMF (30 mg/ml)

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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