BMX-IN-1

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Cat No.

CEI-1258

Description

BMX-IN-1 is a highly selective and potent irreversible inhibitor of BMX kinase.

Product Overview

BMX-IN-1 is a highly selective and irreversible inhibitor of BMX kinase. BMX, also known as ETK, is a member of Tec family and plays an important role in regulating ischemia-mediated arteriogenesis and lymphangiogenesis. BMX is mainly expressed in arterial endothelia and in myeloid hematopoietic cells and it has been reported that BMX involves in tumor growth. BMX-IN-1 is a potent BMX kinase inhibitor and has an irreversible function on BMX kinase. When tested with prostate cancer cell lines, BMX-IN-1 treatment inhibited the proliferation of Tel-BMX-transformed Ba/F3 cells at lowdose.

CAS_No

1431525-23-3

Molecular Weight

524.59

Purity

0.982

Storage

Store at -20°C

Synonyms

BMX kinase inhibitor

Targets

BMX kinase

Molecular Formula

C29H24N4O4S

Chemical Name

N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]prop-2-enamide

Solubility

Soluble in DMSO

Shipping Conditions

Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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