Borrelidin

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Cat No.

CEI-0401

Description

A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC50 = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor.

Alias

Treponemycin; U 78548; C2989

Appearance

White to off-white solid

Product Overview

An angiogenesis inhibitor

CAS_No

7184-60-3

Molecular Weight

274.18

Purity

>99%

Storage

-20 centigrade

Synonyms

Treponemycin; U 78548; C2989

Targets

Angiogenesis

Molecular Formula

C 28 H 43 NO 6

Solubility

DMSO (~ 5 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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