Calpain Inhibitor II, ALLM

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Cat No.

CEI-0412

Description

A cell-permeable inhibitor of calpain 1 (Ki = 120 nM) and calpain 2 (Ki = 230 nM). Also potently inhibits cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Shown to induce caspase-dependent apoptosis in human acute lymphoblastic leukemia and non-Hodgkin’s Lymphoma cells.

Alias

Ac-LLM-CHO, N-Acetyl-Leu-Leu-Methional

Appearance

White solid

Product Overview

A Calpain inhibitor

CAS_No

136632-32-1

Molecular Weight

404.54

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

Ac-LLM-CHO, N-Acetyl-Leu-Leu-Methional

Targets

calpain I, calpain II

Molecular Formula

C₁₉H₃₅N₃O₄S

Solubility

DMSO (25 mg/ml) or Ethanol (30 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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