Camptothecin

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Cat No.

CEI-0681

Description

Reversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat, osteosarcoma and hepatoma cells.

Appearance

Liquid

Product Overview

A topoisomerase I inhibitor

CAS_No

7689-03-4

Molecular Weight

513.49

Purity

>95% by HPLC

Storage

-20 centigrade

Targets

TOP1MT

Molecular Formula

C₂₀H₁₆N₂O₄

Chemical Name

(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

Solubility

A 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh in DMSO.

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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