chloramphenicol O-acetyltransferase

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Cat No.

EXWM-2205

Description

Chloramphenicol acetyltransferase (or CAT) is a bacterial enzyme (EC 2.3.1.28) that detoxifies the antibiotic chloramphenicol and is responsible for chloramphenicol resistance in bacteria. This enzyme covalently attaches an acetyl group from acetyl-CoA to chloramphenicol, which prevents chloramphenicol from binding to ribosomes. A histidine residue, located in the C-terminal section of the enzyme, plays a central role in its catalytic mechanism.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 2.3.1.28

CAS_No

9040-07-7

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

chloramphenicol acetyltransferase; chloramphenicol acetylase; chloramphenicol transacetylase; CAT I; CAT II; CAT III

Reaction

acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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