chondroitin AC lyase

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Cat No.

EXWM-5104

Description

Acts on chondroitin 4-sulfate and chondroitin 6-sulfate, but less well on hyaluronate. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycan source.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 4.2.2.5

CAS_No

9047-57-8

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC

Reaction

Eliminative degradation of polysaccharides containing 1,4-β-D-hexosaminyl and 1,3-β-D-glucuronosyl linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"ChnAC" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1738	Chondroitinase AC from Flavobacterium heparinum, Recombinant	EC 4.2.2.5	9047-57-8	E. coli	Inquiry
NATE-0126	Native Flavobacterium heparinum Chondroitinase AC	EC 4.2.2.5	9047-57-8	Flavobacterium heparinum	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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