CMP-Sialic Acid, Monosodium Salt

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Cat No.

CSUB-0778

Description

CMP-sialic acid, Monosodium salt is the active form of sialic acid. In mammalian cells it has been shown to be required for the biosynthesis of sialic acid-containing complex carbohydrates. Loss of CMP sialic acid, Monosodium salt production or the feed back inhibitor of CMP-sialic acid has lead to gram scale production of sialic acid by GLCNE (GNE, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase). The compound has demonstrated the ability to neutralize various toxins through masking binding sites. CMP-sialic acid, Monosodium salt has also provided protection against gonococci by siaylation of Gal beta 1-4GlcNAc group. Catalyzed through a surface sialyl-transferase, CMP-Sialic Acid, Monosodium Salt enhanced the responsiveness of insulin. The compound has also displayed function in blood protein half-life regulation, protection against glycoprotein lysis and cellular adhesion. CMP-Sialic Acid, Monosodium Salt is a substrate of Sialyltransferase.

Applications

A toxin/gonococci protector; blood regulator

Form

Solid

CAS_No

3063-71-6

Molecular Weight

636.43

Purity

>85%

Storage

Store at -20° C

Synonyms

CMP-N-Acetylneuraminic Acid, Na

Molecular Formula

C20H30N4O16P·Na

MDL Number

MFCD00151579

Solubility

Soluble in water.

Substrates

Collagenase

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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