CMP-Sialic Acid Synthetase from Neisseria meningitidis group B, Recombinant

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Cat No.

NATE-0023

Description

In enzymology, a N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) is an enzyme that catalyzes the chemical reaction:CTP + N-acylneuraminate↔ diphosphate + CMP-N-acylneuraminate. Thus, the two substrates of this enzyme are CTP and N-acylneuraminate, whereas its two products are diphosphate and CMP-N-acylneuraminate. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). This enzyme participates in aminosugars metabolism.

Abbr

Acid Synthetase, Recombinant (Neisseria meningitidis group B)

Source

E. coli BL21

Species

Neisseria meningitidis group B

Applications

The enzyme has been utilized to synthesize CMP-sialic acid and its derivatives.

Form

, Supplied as a lyophilized powder containing Tris-HCl and NaCl.

Enzyme Commission Number

EC 2.7.7.43

Activity

> 10 units/mg protein

CAS_No

9067-82-7

Unit Definition

One unit will catalyze the formation of 1 μmol CMP-Neu-5-Ac from Neu-5-Ac and CTP per minute at 37°C at pH 8.0.

Storage

−20°C

Synonyms

EC 2.7.7.43; N-acylneuraminate cytidylyltransferase; CMP-sialate pyrophosphorylase; CMP-sialate synthase; cytidine 5'-monophosphosialic acid synthetase; CMP-Neu5Ac synthetase; CMP-NeuAc synthetase; acylneuraminate cytidyltransferase; CMP-N-acetylneuraminate synthetase; CMP-N-acetylneuraminate synthase; CMP-N-acetylneuraminic acid synthase; CMP-NANA synthetase; CMP-sialate synthetase; CMP-sialic synthetase; cytidine 5'-monophospho-N-acetylneuraminic acid synthetase; cytidine 5-monophosphate N-acetylneuraminic acid synthetase; cytidine monophosphosialic acid synthetase; cytidine monophosphoacetylneuraminic synthetase; cytidine monophosphosialate pyrophosphorylase; cytidine monophosphosialate synthetase; acetylneuraminate cytidylyltransferase

"Acid Synthetase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
EXWM-3255	N-acylneuraminate cytidylyltransferase	EC 2.7.7.43	9067-82-7		Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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