Compound E

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Cat No.

CEI-0707

Description

Cell-permeable. A potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC50 = 0.3 nM for total β-amyloid) and Notch processing. At higher concentrations (20-400 µM), only weakly affects the presenilase activity.

Appearance

White solid

Product Overview

A potent, selective inhibitor of γ-secretase

CAS_No

209986-17-4

Molecular Weight

465.76

Purity

>85% by HPLC

Storage

-20 centigrade

Targets

gamma-secretase

Molecular Formula

C₂₇H₂₄F₂N₄O₃

Chemical Name

(2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide

Solubility

10 mM HCl

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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