CYC-116

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Cat No.

CEI-1095

Description

CYC116 is an orally active small molecule multi-kinase inhibitor with antineoplastic activity. CYC116 inhibits Aurora kinases A and B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death.

Abbr

CYC-116(AURKA, AURKB, KDR)

Alias

RP5-1167H4.6, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7

Product Overview

Inhibits Aurora kinases A and B and vascular endothelial growth factor receptor 2 (VEGFR2)

CAS_No

693228-63-6

Molecular Weight

368.46

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

-20 centigrade

Synonyms

RP5-1167H4.6, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7

Targets

Aurora kinases A, Aurora kinases B, vascular endothelial growth factor receptor 2 (VEGFR2)

Molecular Formula

C18H20N6OS

Chemical Name

4-(2-amino-4-methylthiazol-5-yl)-N-(4-morpholinophenyl)pyrimidin-2-amine

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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