cyclic-guanylate-specific phosphodiesterase

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Cat No.

EXWM-3735

Description

Requires Mg2+ or Mn2+ for activity and is inhibited by Ca2+ and Zn2+. Contains a heme unit. This enzyme linearizes cyclic di-3,5-guanylate, the product of EC 2.7.7.65, diguanylate cyclase and an allosteric activator of EC 2.4.1.12, cellulose synthase (UDP-forming), rendering it inactive. It is the balance between these two enzymes that determines the cellular level of c-di-GMP.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.1.4.52

CAS_No

338732-46-0

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

cyclic bis(3→5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA

Reaction

cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'→5')guanosine

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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