Products

Enzymes for Research, Diagnostic and Industrial Use

Products
Online Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

24 hour
Promise

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Cytochrome P450 Reductase from Human, Recombinant

Cat No.
NATE-1586
Description
Cytochrome P450 reductase is a membrane bound enzyme required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. The cytochrome P450 enzyme system is mainly involved in the detoxification of xenobiotics in the liver. It also participates in the activation of procarcinogens and the metabolism of endogeneous substrates such as steroids.
Abbr
CPR, Recombinant (Human)
Alias
CPR
Source
Baculovirus infected insect cells
Species
Human
Applications
Human cytochrome P450 reductase has been used in a study to assess the biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat. Human cytochrome P450 reductase has also been used in a study to investigate the effects of coupled motions on electrons along the human microsomal P450 chains.
Form
Supplied in a solution containing 10 mM potassium phosphate, pH 7.4, 0.1 mM EDTA, 0.5 mM DTT, 20% (v/v) glycerol
Enzyme Commission Number
EC 1.6.2.4
Activity
>30 U/mg
CAS No.
9023-03-4
Molecular Weight
76.5 kDa
Purity
>90% (SDS-PAGE)
Concentration
>1.0 mg/mL
Unit Definition
One unit will cause the reduction of 1.0 μmole of cytochrome c by NADPH per minute at pH 7.4 at 37 °C.
Storage
Store at -70°C
Synonyms
EC 1.6.2.4; NADPH:ferrihemoprotein oxidoreductase; NADPH:hemoprotein oxidoreductase; NADPH:P450 oxidoreductase; P450 reductase; CPR; 9039-06-9; FAD-cytochrome c reductase; NADPH-dependent cytochrome c reductase; NADPH:P-450 reductase

"CPR" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-0158 Native Rabbit Cytochrome P450 Reductase induced with phenobarbital EC 1.6.2.4 9023-82-9 Rabbit liver Inquiry
EXWM-1580 NADPH-hemoprotein reductase EC 1.6.2.4 9023-03-4 Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

0
Click unfold / close
Inquiry Basket
Delete selected Quote Check Out
Decide to move out of the shopping cart?
Sure No, Back

Please choose product!

< Go Back
You have already added to buy this product