diguanylate cyclase

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Cat No.

EXWM-3276

Description

A GGDEF-domain-containing protein that requires Mg2+ or Mn2+ for activity. The enzyme can be activated by BeF3, a phosphoryl mimic, which results in dimerization. Dimerization is required but is not sufficient for diguanylate-cyclase activity. Cyclic di-3',5'-guanylate is an intracellular signalling molecule that controls motility and adhesion in bacterial cells. It was first identified as having a positive allosteric effect on EC 2.4.1.12, cellulose synthase (UDP-forming).

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 2.7.7.65

CAS_No

146316-82-7

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

DGC; PleD

Reaction

2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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