Epoxomicin

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Cat No.

CEI-0627

Description

Originally isolated from Actinomycetes strain based on its potent in vivo antitumor activity, Epoxomicin is a potent, cell-permeable, selective and irreversible proteasome inhibitor. More potent inhibitor of the chymotrypsin-like activity of the proteasome than Lactacystin. Blocks also trypsin-like and PGPH activities of the proteasome.

Alias

BU-4061T

Appearance

Off-white solid

Product Overview

A potent proteasome inhibitor

CAS_No

134381-21-8

Molecular Weight

248.23

Purity

~80% by TLC

Storage

-20 centigrade

Synonyms

BU-4061T

Targets

Proteasome

Molecular Formula

C28H50N4O7

Chemical Name

N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl- 1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-threoninamide

Solubility

H₂O (200 mg/ml) or MeOH (50 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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