F-actin monooxygenase

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Cat No.

EXWM-0828

Description

The enzyme, characterized from the fruit fly Drosophila melanogaster, is a multi-domain oxidoreductase that acts as an F-actin disassembly factor. The enzyme selectively reduces two L-Met residues of F-actin, causing fragmentation of the filaments and preventing repolymerization. Free methionine is not a substrate. The reaction is stereospecific and generates the (R)-sulfoxide.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 1.14.13.225

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

MICAL (gene name)

Reaction

[F-actin]-L-methionine + NADPH + O2 + H+ = [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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