FK-506

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Cat No.

CEI-0540

Description

A potent immunosuppresant and in vitro T cell proliferation blocker. It disrupts calcineurin-mediated signal transduction in T-lymphocytes. It interacts with its FK506-binding protein-12 (FKBP-12), leading to increase in the release of sarcoplamic reticulum-derived calcium. FK506 and rapamycin, but not cytosporin inhibit aldosterone-stimulated sodium transport in A6 cells.

Alias

Tacrolimus

Appearance

White solid

Product Overview

A potent immunosuppresant

CAS_No

104987-11-3

Molecular Weight

805

Purity

>98%

Storage

-20 centigrade

Synonyms

Tacrolimus

Targets

immunosuppresant

Molecular Formula

C₄₄H₆₉NO₁₂

Chemical Name

Tacrolimus

Solubility

DMSO (>1 mg/ml) and EtOH (>1 mg/ml)

Shipping Conditions

Gel pack

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