Fluorouracil

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Cat No.

CEI-0320

Description

Adrucil

Alias

5-Fluoracil, 5-FU, NSC19893

CAS_No

51-21-8

Molecular Weight

130.08

Purity

>99%

Storage

2 years -20centigrade Powder

Synonyms

5-Fluoracil, 5-FU, NSC19893

Targets

Thymidylate synthase

Molecular Formula

C4H3FN2O2

Chemical Name

5-Fluor-2,4-dihydroxypyrimidin

Solubility

DMSO 26 mg/mL, Water

In vitro

Adrucil is an DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS). Adrucil metabolite FdUMP binds to the nucleotide-binding site of TS, forming a stable ternary complex with the enzyme and CH2THF.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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