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Enzymes for Research, Diagnostic and Industrial Use

Fmoc-α-methyl-L-glutamic Acid γ-tert-butyl Ester

Cat No.
CEGZ-6858
Description
Fmoc-α-methyl-L-glutamic acid γ-tert-butyl ester is an α-methylated, side-chain-protected glutamic acid building block used in Fmoc solid-phase peptide synthesis.
Applications
Fmoc solid-phase peptide synthesis
α-Methyl amino acid building block
Laboratory research and development
Product Overview
Fmoc-α-Me-Glu(OtBu)-OH carries the Fmoc group on the α-amino function, an additional methyl group at the α-carbon, and an acid-labile tert-butyl ester on the γ-carboxyl group. The quaternary α-carbon restricts backbone conformation and enhances proteolytic stability; due to steric hindrance, coupling typically requires stronger activation or extended reaction times.
CAS_No
1072845-48-7
Molecular Weight
439.5
Storage
Store in a tightly closed container in a cool, dry place.
Synonyms
Fmoc-α-Me-Glu(OtBu)-OH
Molecular Formula
C25H29NO6
Notes
For research and development use only.

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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