Fmoc-S-acetamidomethyl-L-penicillamine

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Cat No.

CEGZ-6752

Description

Fmoc-S-acetamidomethyl-L-penicillamine is a side-chain-protected penicillamine building block used in Fmoc solid-phase peptide synthesis, particularly for disulfide-bond strategies.

Applications

Fmoc solid-phase peptide synthesis
Peptide synthesis building block
Laboratory research and development

Product Overview

Fmoc-Pen(Acm)-OH carries base-labile Fmoc protection on the α-amino group and an acetamidomethyl (Acm) group on the thiol of penicillamine, a β,β-dimethylcysteine. The gem-dimethyl substitution restricts local conformation, and the Acm group is stable to TFA cleavage, allowing regioselective disulfide bond formation through subsequent iodine-mediated oxidation.

CAS_No

201531-76-2

Molecular Weight

442.5

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-Pen(Acm)-OH

Molecular Formula

C23H26N2O5S

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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