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Fumagillin
Cat No.
CEI-0402
Description
Fumagillin is a meroterpenoid antibiotic isolated from Aspergillus fumigatus. An anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo.
Alias
Amebacilin; Fugilin; Fumidil; Fumadil B; NSC9168; U5762
Appearance
White to off-white solid
Product Overview
An angiogenesis inhibitor
CAS No.
23110-15-8
Molecular Weight
432.46
Purity
>98% by TLC
Storage
-20 centigrade
Synonyms
Amebacilin; Fugilin; Fumidil; Fumadil B; NSC9168; U5762
Targets
Angiogenesis
Molecular Formula
C 26 H 34 O 7
Solubility
DMSO (~20 mg/ml)
Shipping Conditions
Gel pack
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