GANT58

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Cat No.

CEI-0520

Description

Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC50 ~ 5 µM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative and antitumor activity in vivo.

Alias

NSC75503

Appearance

Off-white solid

Product Overview

A Hedgehog (Hh) signaling pathway inhibitor

CAS_No

64048-12-0

Molecular Weight

341.4

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

NSC75503

Targets

Molecular Formula

C₂₄H₁₆N₄S

Chemical Name

2,3,4,5-Tetra(4-pyridyl)thiophene

Solubility

DMSO

Shipping Conditions

Gel Pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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