GANT61

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Cat No.

CEI-0521

Description

Cell-permeable. A Hedgehog (Hh) signaling pathway antagonist. Inhibits Hh signaling downstream of Smo and Sufu at the level of Gli (IC50 = 5 µM). GANT61 has also been shown to inhibit the in vitro proliferation of PANC1 and 22Rv1 cells which have elevated GLi11 levels and prevent the development of 22Rv1 tumors in mice.

Alias

NSC 136476

Appearance

White solid

Product Overview

A Hedgehog (Hh) signaling pathway antagonist

CAS_No

500579-04-4

Molecular Weight

258.23

Purity

>98% by TLC

Storage

-20 centigrade

Synonyms

NSC 136476

Targets

Molecular Formula

C₂₇H₃₅N₅

Chemical Name

2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis(N,N-dimethyl-benzenamine)

Solubility

DMSO (5 mg/ml)

Shipping Conditions

Gel pack

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Project Description

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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