Geranylgeranyltransferase from rat, Recombinant

inquiry

Cat No.

NATE-0285

Description

Geranylgeranyltransferase type 1 or simply geranylgeranyltransferase is one of the three enzymes in the prenyltransferase group. In specific terms, Geranylgeranyltransferase (GGTase 1) adds a 20-carbon isoprenoid called a geranylgeranyl group to proteins bearing a CaaX motif:a four-amino acid sequence at the carboxyl terminal of a protein. Geranylgeranyltransferase inhibitors are being investigated as anti-cancer agents.

Abbr

GGTase, Recombinant (Rat)

Alias

GGTase-I; GGTase

Source

E. coli

Species

Rat

Form

Solution

Activity

1 pmol of GGTase-I will transfer 5 pmol of Farnesyl to RhoA in 15 min at 37°C.

CAS_No

160141-09-3

Molecular Weight

38 kDa (β subunit), 44 kDa (α subunit)

Purity

> 90 % (SDS-PAGE)

Stability

Store at -80 °C, avoid freeze/thaw cycles. Shelf Life: 12 months

Buffer

Supplied in 50 mM HEPES pH 7.4, 40 mM NaCl, 1 mM TECP and 5 μM ZnCl2.

Synonyms

geranylgeranyltransferase type I; GGTase-I; GGTase; 160141-09-3; Geranylgeranyltransferase

"GGTase" Total Products Page

Name:

Email *

Phone:*

Company/Institution:

Country or Region:

Quantity:

Services & Products Interested *

Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Products

Online Inquiry