Glucokinase from Human, recombinant

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Cat No.

NATE-1686

Description

Glucose is phosphorylated to glucose-6-phosphate by glucokinases. This gene is alternatively spliced to generate three different forms of the enzyme; one found in the pancreas and two found in the liver. The main function of this gene is to regulate carbohydrate metabolism. Recombinant human Glucokinase produced in E.Coli is a single, non-glycosylated polypeptide chain containing 485 amino acids (1-465 a.a) and having a molecular mass of 54.3kDa. GCK is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Abbr

GCK, Recombinant (Human)

Source

E. coli

Species

Human

Form

Liquid

Enzyme Commission Number

EC 2.7.1.2

Activity

> 2,000 pmol/min/ug

CAS_No

9001-36-9

Molecular Weight

54.3kDa

Purity

> 95% by SDS-PAGE

Concentration

1 mg/ml

Unit Definition

One unit will convert 1 pmoles of D-Glucose to D-Glucose-6-phosphate per minute at pH8.0 at 37°C.

Storage

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Synonyms

EC 2.7.1.2; glucokinase; glucokinase (phosphorylating); 9001-36-9; GCK; FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2; Hexokinase type IV; HK IV; Hexokinase-4; Hexokinase-D

Formulation

GCK protein solution (1mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0) and 10% glycerol.

"GCK" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1687	Glucokinase from Human, recombinant	EC 2.7.1.2	9001-36-9	E. coli	Inquiry
NATE-1696	Glucokinase from Human, recombinant	EC 2.7.1.2	9001-36-9	E. coli	Inquiry
NATE-1697	Glucokinase from Human, recombinant	EC 2.7.1.2	9001-36-9	E. coli	Inquiry
NATE-1903	Native Zymomonas mobilis Glucokinase	EC 2.7.1.2	9001-36-9	Zymomonas mobilis	Inquiry

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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