GNE 477

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Cat No.

CEI-1138

Description

GNE 477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 value of 4nmol/L and 21nmol/L respectively.

Abbr

GNE 477(PIK3CA, MTOR)

Alias

CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha

CAS_No

1032754-81-6

Molecular Weight

504.63

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha

Targets

PI3K, mTOR

IC50

4nmol/L, 21nmol/L

Molecular Formula

C21H28N8O3S2

Chemical Name

5-(7-methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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