GSK256066

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Cat No.

CEI-0231

Description

GSK256066

CAS_No

801312-28-7

Molecular Weight

518.58

Purity

>99%

Storage

2 years at -20 centigrade

Targets

PDE4B

Molecular Formula

C27H26N4O5S

Solubility

In vitro

GSK256066 is a slow and tight binding inhibitor of PDE4B with apparent IC50 of 3.2 pM. GSK256066 is an extremely potent inhibitor of LPS-stimulated TNFalpha production in PBMCs with pIC50 of 11.0 and IC50 of 10 pM and human whole-blood cultures with pIC50 of 9.90 and IC50 of 126 pM.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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