GSK-J4 hydrochloride

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Cat No.

CEI-0547

Description

Cell-permeable. An ethyl ester derivative of the JMJD3 selective histone demethylase inhibitor GSK-J1 (IC50> 50 µM in vitro. When administered to human primary macrophages, GSK-J4 can reduce lipopolysaccharide (LPS)-induced proinflammatory cytokine production, most notably including that of TNFα (IC50 = 9 µM).

Appearance

Liquid

Product Overview

Histone demethylase JMJD3/UTX inhibitor

CAS_No

1797983-09-5

Molecular Weight

540.54

Purity

>95% by HPLC

Storage

-20 centigrade

Targets

KDM6B

Molecular Formula

C24H27N5O2 . HCL

Chemical Name

Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2--(pyridin-2- yl)pyrimidin-4-yl)amino)propanoate, monohydrochloride

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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